Projets transversaux

> APPEL A PROJETS

Projets transversaux Le LabEx BRAIN lance des appels à projets afin d'approfondir et d'élargir les collaborations intra-Bordeaux Neurocampus. Tous les sujets scientifiques visant à améliorer nos connaissances en Neurosciences sont éligibles pour cet appel à projets. Néanmoins, les domaines scientifiques d'excellence du LabEx BRAIN restent prioritaires.

> LAUREATS

2017

AMPA-MO-CO : Role of AMPA receptor mobility in hippocampal spatial coding and learning

Investigateurs : Humeau (IINS), Bontempi (IMN)

Subvention LabEx : 120 000 €

MesoPOM' : Role of the pro-opio-melanocortin (POMC)-mesolimbic neurocircuit in the development of diet-induced obesity

Investigateurs : Cota (NCM), Fioramonti (NutriNeuro)

Subvention LabEx : 120 000 €

M-REX : Multi-scale analysis of remodeling of brain extracellular space after traumatic brain injury: focus on astroglial mechanisms

Investigateurs : Nägerl (IINS), Badaut (INCIA), Marsicano (NCM)

Subvention LabEx : 120 000 €

MuGly : Mechanisms underlying glycine compartmentalization in the extracellular space: identification and functional role

Investigateurs : Groc (IINS), Oliet (NCM), Castanon (NutriNeuro)

Subvention LabEx : 120 000 €

NANOSYNSLICE : Nanoscale imaging of synaptic molecules in brain slices

Investigateurs : Sibarita (IINS), Sans (NCM)

Subvention LabEx : 120 000 €

NewbornRndEndo : Regulation of membrane trafficking by Rnd2 in newborn neurons of the adult hippocampus

Investigateurs : Pacary (NCM), Perrais (IINS)

Subvention LabEx : 120 000 €

PDPAIN : Understanding the pathophysiology of pain in Parkinson’s disease

Investigateurs : Benazzouz (IMN), Fossat (IINS)

Subvention LabEx : 120 000 €

PIPAIS : Interplay between scribble and the phosphoinositide metabolism controls the AIS structure and the axonal excitability

Investigateurs : Montcouquiol/Sans (NCM), Brachet (IINS)

Subvention LabEx : 120 000 €

SLOWSYN : Enhancing slow wawe sleep to mitigate synucleinopathy and neurodegeneration in parkinson’s disease and multiple system atrophy models

Investigateurs : Bézard (IMN), Nadjar (NutriNeuro), Philip (SanPsy)

Subvention LabEx : 120 000 €

SYNOPTOGENESIS : Optogenetic tuning of the synaptic excitation/inhibition balance through neuroligin phosphorylation

Investigateurs : Thoumine (IINS), Georges (IMN)

Subvention LabEx : 120 000 €

2016

AstroMachine : Identifying the Astrocytic Ca²⁺-signalling machinery governing synaptic plasticity

Investigateurs : Oliet (NCM), Nägerl (IINS), Massa (NCM)

Subvention LabEx : 120 000 €

Astrosome : Is the exosome secretion a new astrocyte-neuron communication pathway?

Investigateurs : Favereaux (IINS), Panatier (NCM)

Subvention LabEx : 120 000 €

DoLipran : Exploring the vulnerability of the dopaminergic synaptic membrane to lipid manipulations: from molecular origin to behavioral consequences

Investigateurs : Trifilieff (NutriNeuro), Herzog (IINS)

Subvention LabEx : 120 000 €

DopaNet-GOAL : Dopaminergic control of neuronal networks dynamics during goal-directed behaviors

Investigateurs : Mallet (IMN), Gambino (IINS)

Subvention LabEx : 105 000 €

FEARLESSPAIN : Neuronal circuits of fear conditioned analgesia

Investigateurs : Fossat (IINS), Herry (NCM)

Subvention LabEx : 120 000 €

HippoMeal : Cellular mechanisms underlying hippocampal regulation of feeding behavior

Investigateurs : Carta (IINS), Ferreira (NutriNeuro), Busquets-Garcia (NCM)

Subvention LabEx : 117 000 €

MotivRun : Are cannabinoid receptors on glutamatergic neurons involved in the imbalance between the motivational drives for feeding and running in restrictive anorexia?

Investigateurs : Chaouloff (NCM), Georges (IMN)

Subvention LabEx : 120 000 €

P2XforALS : Unraveling the implication of P2X4 purinoceptors in amyotrophic lateral sclerosis (ALS) pathogenesis

Investigateurs : Boué-Grabot (IMN), Bertrand (INCIA)

Subvention LabEx : 112 000 €

PCP Compass : PCP signaling control of young neurons growth: from nanoscale analysis to directed motility

Investigateurs : Montcouquiol/Sans (NCM), Studer (IINS)

Subvention LabEx : 120 000 €

2014

Astradict : Is stress-induced vulnerability to drug of abuse an astrocyte-dependent process?

Investigateurs : Panatier (NCM), Piazza (NCM), Georges (IINS)

Subvention LabEx : 120 000 €

CannaCalc : Modulation of synaptic calcium signaling by mitochondrial type 1 cannabinoid receptor

Investigateurs : Pouvreau (IINS), Massa (NCM)

Subvention LabEx : 120 000 €

CortMem : Neuron-type specific cellular mechanisms underlying the organization of recent and remote memories in the normal and diseased brain

Investigateurs : Frick (NCM), Bontempi (IMN)

Subvention LabEx : 113 400 €

DOPABED : Functional characterization of a dopaminergic projection to the bed nucleus of the stria terminalis during aversive learning

Investigateurs : Georges (IINS), Herry (NCM)

Subvention LabEx : 120 000 €

ExtraBrain : Exploring the brain extracellular space dynamics in physiology and pathology

Investigateurs : Groc (IINS), Bézard (IMN), Cognet (LAPHIA), Blanchard-Desce (LAPHIA)

Subvention LabEx : 100 000 €

MEMO-MS : Pathophysiology and imaging biomarker of memory impairment in early multiple sclerosis – from animal model to patients

Investigateurs : Tourdias (NCM), Hiba (TRAIL)

Subvention LabEx : 119 190 €

NanoPain : Nanoparticles as a carrier of bioactive peptide against pain sensitization

Investigateurs : Landry (IINS), Heroguez (AMADEUS)

Subvention LabEx : 60 000 €

NeuroAge : Comparison of the plastic properties of adult-born and developmentally-born granule dentate neurons

Investigateurs : Abrous (NCM), Mulle (IINS)

Subvention LabEx : 100 000 €

NEUROCONTEXT : Neuronal circuits of contextual fear

Investigateurs : Humeau (IINS), Herry (NCM)

Subvention LabEx : 118 000 €

OntoMemo : Contribution of the dentate gyrus to the ontogeny of learning and memory skills

Investigateurs : Koehl (NCM), Georges (IINS)

Subvention LabEx : 100 000 €

SuperClass : New methods of aquisition ad classification for high content screening of membrane receptor organization and dynamics using super-resolution microscopy

Investigateurs : Sibarita (IINS), Domenger (CPU)

Subvention LabEx : 120 000 €

2013

Deciphering the mechanisms of central pain sensitization in vivo using innovative heat-shock local deletion of the L-type calcium channel Cav1.2 gene in the mouse lumbar bulge

Investigateurs : Baudet (IINS), Fossat (IINS), Quesson (CNRS UMS 3428), Petry (INSERM U1049), Dumont (Image Guided Therapy)

Subvention LabEx : 86 600 €

Determining the mode of binding of PSD-95 tandem PDZ domains

Investigateurs : Sainlos (IINS), Mackereth (IECB)

Subvention LabEx : 94 000 €

Does the orexin system corntibute to individual differences in sleep deprivation-induced changes in neurobehavioral function

Investigateurs : Philip (Sanpsy), Layé (NutriNeuro)

Subvention LabEx : 45 000 €

Membrane dynamics of astrocytic glutamate transporter and its functional impact on synaptic functions

Investigateurs : Groc (IINS), Oliet (NCM)

Subvention LabEx : 63 332 €

Relative contribution of the hypothalamic proliferative and neuroinflammatory responses to the obese phenotype

Investigateurs : Cota (NCM), Abrous (NCM), Layé (NutriNeuro)

Subvention LabEx : 49 000 €

Role of neuronal and astroglial CB1 receptors in morpho-functional plasticity of the tripartite synapse

Investigateurs : Marsicano (NCM), Nägerl (IINS)

Subvention LabEx : 63 332 €

Role of planar polarity proteins on the cytoskeleton dynamics of dendritic spines

Investigateurs : Montcouquiol/Sans (NCM), Thoumine (IINS)

Subvention LabEx : 63 332 €

Study of miRNA expression pattern as diagnostic and prognostic biomarker in Amyotrophic Lateral Sclerosis

Investigateurs : Favereaux (IINS), Le Masson (NCM), Wielanek-Bachelet (Centre référence SLA)

Subvention LabEx : 88 000 €

The impact of structural changes in axons on information transfert in CA3 neurons:a combined computational and nanoscale imaging study

Investigateurs : Cattaert (INCIA), Nägerl (IINS)

Subvention LabEx : 20 000 €

Thermo-sensitive nanoparticules as a carrier of bioactive peptide against pain sensitization Determining the mode of binding of PSD-95 tandem PDZ domains

Investigateurs : Landry (IINS), Heroguez (CNRS UMR 5629), Petry (INSERM U1049)

Subvention LabEx : 86 600 €

Translational study of the cerebral substrates involved in pathological fear recovery

Investigateurs : Herry (NCM), Bonnet (UMS CNRS 3428)

Subvention LabEx : 70 000 €

2012

Biobanque

Investigateurs : Bézard (IMN), Meissner (IMN)

Subvention LabEx : 50 000 €

Characterization of molecular pathways involved in vulnerability to drug addiction

Investigateurs : Revest (NCM)

Subvention LabEx : 40 000 €

Characterization of neuronal circuits involved in addiction

Investigateurs : Herry (NCM)

Subvention LabEx : 40 000 €

CytoPlan : Impact of planar polarity on shaping neurons and synapses

Investigateurs : Montcouquiol/ Sans (NCM), Thoumine (IINS)

Subvention LabEx : 36 000 €

Dippal : Diagnostic précoce et pléothérapie de la maladie d'Alzheimer

Investigateurs : Orgogozo (SanPsy), Philip (SanPsy)

Subvention LabEx : 45 000 €

Functional contribution of newly born neurons to the formation of remote memories during normal aging

Investigateurs : Abrous (NCM), Bontempi (IMN)

Subvention LabEx : 70 014 €

Morpho-functional plasticity of the tripartite synapse

Investigateurs : Marsicano (NCM), Nägerl (IINS), Oliet (NCM)

Subvention LabEx : 58 000 €

Programming support for dynamic clamp hybrid systems applications

Investigateurs : Simmers (INCIA), Lemasson (NCM), Cattaert (INCIA)

Subvention LabEx : 68 000 €

Psychobehavioral characterization of addiction

Investigateurs : Cota (NCM), Deroche-Gamonet (SanPsy)

Subvention LabEx : 20 000 €

SCOAL : Sleep, cognition and Alzheimer

Investigateurs : Philip (SanPsy)

Subvention LabEx : 45 000 €

Unraveling the anatomical wiring diagram to understand the physiology and pathophysiology of the hippocampus and neocortex

Investigateurs : Mulle (IINS), Frick (NCM)

Subvention LabEx : 116 000 €