Transversal projects
> CALL FOR PROPOSALS
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The LabEx BRAIN launches calls for proposals in order to deepen and enlarge intra-Bordeaux Neurocampus collaborations. All the scientific topics aiming at improving our knowledge in neuroscience are eligible to this open call for proposal. Nevertheless, the LabEx BRAIN scientific areas of excellence remain priorities.
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> LAUREATES
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- 2017
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AMPA-MO-CO : Role of AMPA receptor mobility in hippocampal spatial coding and learning
Investigators : Humeau (IINS), Bontempi (IMN)
LabEx grant : 120 000 €
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MesoPOM' : Role of the pro-opio-melanocortin (POMC)-mesolimbic neurocircuit in the development of diet-induced obesity
Investigators : Cota (NCM), Fioramonti (NutriNeuro)
LabEx grant : 120 000 €
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M-REX : Multi-scale analysis of remodeling of brain extracellular space after traumatic brain injury: focus on astroglial mechanisms
Investigators : Nägerl (IINS), Badaut (INCIA), Marsicano (NCM)
LabEx grant : 120 000 €
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MuGly : Mechanisms underlying glycine compartmentalization in the extracellular space: identification and functional role
Investigators : Groc (IINS), Oliet (NCM), Castanon (NutriNeuro)
LabEx grant : 120 000 €
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NANOSYNSLICE : Nanoscale imaging of synaptic molecules in brain slices
Investigators : Sibarita (IINS), Sans (NCM)
LabEx grant : 120 000 €
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NewbornRndEndo : Regulation of membrane trafficking by Rnd2 in newborn neurons of the adult hippocampus
Investigators : Pacary (NCM), Perrais (IINS)
LabEx grant : 120 000 €
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PDPAIN : Understanding the pathophysiology of pain in Parkinson’s disease
Investigators : Benazzouz (IMN), Fossat (IINS)
LabEx grant : 120 000 €
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PIPAIS : Interplay between scribble and the phosphoinositide metabolism controls the AIS structure and the axonal excitability
Investigators : Montcouquiol/Sans (NCM), Brachet (IINS)
LabEx grant : 120 000 €
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SLOWSYN : Enhancing slow wawe sleep to mitigate synucleinopathy and neurodegeneration in parkinson’s disease and multiple system atrophy models
Investigators : Bézard (IMN), Nadjar (NutriNeuro), Philip (SanPsy)
LabEx grant : 120 000 €
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SYNOPTOGENESIS : Optogenetic tuning of the synaptic excitation/inhibition balance through neuroligin phosphorylation
Investigators : Thoumine (IINS), Georges (IMN)
LabEx grant : 120 000 €
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- 2016
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AstroMachine : Identifying the Astrocytic Ca2+-signalling machinery governing synaptic plasticity
Investigators : Oliet (NCM), Nägerl (IINS), Massa (NCM)
LabEx grant : 120 000 €
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Astrosome : Is the exosome secretion a new astrocyte-neuron communication pathway?
Investigators : Favereaux (IINS), Panatier (NCM)
LabEx grant : 120 000 €
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DoLipran : Exploring the vulnerability of the dopaminergic synaptic membrane to lipid manipulations: from molecular origin to behavioral consequences
Investigators : Trifilieff (NutriNeuro), Herzog (IINS)
LabEx grant : 120 000 €
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DopaNet-GOAL : Dopaminergic control of neuronal networks dynamics during goal-directed behaviors
Investigators : Mallet (IMN), Gambino (IINS)
LabEx grant : 105 000 €
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FEARLESSPAIN : Neuronal circuits of fear conditioned analgesia
Investigators : Fossat (IINS), Herry (NCM)
LabEx grant : 120 000 €
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HippoMeal : Cellular mechanisms underlying hippocampal regulation of feeding behavior
Investigators : Carta (IINS), Ferreira (NutriNeuro), Busquets-Garcia (NCM)
LabEx grant : 117 000 €
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MotivRun : Are cannabinoid receptors on glutamatergic neurons involved in the imbalance between the motivational drives for feeding and running in restrictive anorexia?
Investigators : Chaouloff (NCM), Georges (IMN)
LabEx grant : 120 000 €
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P2XforALS : Unraveling the implication of P2X4 purinoceptors in amyotrophic lateral sclerosis (ALS) pathogenesis
Investigators : Boué-Grabot (IMN), Bertrand (INCIA)
LabEx grant : 112 000 €
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PCP Compass : PCP signaling control of young neurons growth: from nanoscale analysis to directed motility
Investigators : Montcouquiol/Sans (NCM), Studer (IINS)
LabEx grant : 120 000 €
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- 2014
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Astradict : Is stress-induced vulnerability to drug of abuse an astrocyte-dependent process?
Investigators : Panatier (NCM), Piazza (NCM), Georges (IINS)
LabEx grant : 120 000 €
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CannaCalc : Modulation of synaptic calcium signaling by mitochondrial type 1 cannabinoid receptor
Investigators : Pouvreau (IINS), Massa (NCM)
LabEx grant : 120 000 €
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CortMem : Neuron-type specific cellular mechanisms underlying the organization of recent and remote memories in the normal and diseased brain
Investigators : Frick (NCM), Bontempi (IMN)
LabEx grant : 113 400 €
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DOPABED : Functional characterization of a dopaminergic projection to the bed nucleus of the stria terminalis during aversive learning
Investigators : Georges (IINS), Herry (NCM)
LabEx grant : 120 000 €
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ExtraBrain : Exploring the brain extracellular space dynamics in physiology and pathology
Investigators : Groc (IINS), Bézard (IMN), Cognet (LAPHIA), Blanchard-Desce (LAPHIA)
LabEx grant : 100 000 €
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MEMO-MS : Pathophysiology and imaging biomarker of memory impairment in early multiple sclerosis – from animal model to patients
Investigators : Tourdias (NCM), Hiba (TRAIL)
LabEx grant : 119 190 €
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NanoPain : Nanoparticles as a carrier of bioactive peptide against pain sensitization
Investigators : Landry (IINS), Heroguez (AMADEUS)
LabEx grant : 60 000 €
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NeuroAge : Comparison of the plastic properties of adult-born and developmentally-born granule dentate neurons
Investigators : Abrous (NCM), Mulle (IINS)
LabEx grant : 100 000 €
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NEUROCONTEXT : Neuronal circuits of contextual fear
Investigators : Humeau (IINS), Herry (NCM)
LabEx grant : 118 000 €
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OntoMemo : Contribution of the dentate gyrus to the ontogeny of learning and memory skills
Investigators : Koehl (NCM), Georges (IINS)
LabEx grant : 100 000 €
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SuperClass : New methods of aquisition ad classification for high content screening of membrane receptor organization and dynamics using super-resolution microscopy
Investigators : Sibarita (IINS), Domenger (CPU)
LabEx grant : 120 000 €
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- 2013
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Deciphering the mechanisms of central pain sensitization in vivo using innovative heat-shock local deletion of the L-type calcium channel Cav1.2 gene in the mouse lumbar bulge
Investigators : Baudet (IINS), Fossat (IINS), Quesson (CNRS UMS 3428), Petry (INSERM U1049), Dumont (Image Guided Therapy)
LabEx grant : 86 600 €
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Determining the mode of binding of PSD-95 tandem PDZ domains
Investigators : Sainlos (IINS), Mackereth (IECB)
LabEx grant : 94 000 €
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Does the orexin system corntibute to individual differences in sleep deprivation-induced changes in neurobehavioral function
Investigators : Philip (Sanpsy), Layé (NutriNeuro)
LabEx grant : 45 000 €
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Membrane dynamics of astrocytic glutamate transporter and its functional impact on synaptic functions
Investigators : Groc (IINS), Oliet (NCM)
LabEx grant : 63 332 €
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Relative contribution of the hypothalamic proliferative and neuroinflammatory responses to the obese phenotype
Investigators : Cota (NCM), Abrous (NCM), Layé (NutriNeuro)
LabEx grant : 49 000 €
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Role of neuronal and astroglial CB1 receptors in morpho-functional plasticity of the tripartite synapse
Investigators : Marsicano (NCM), Nägerl (IINS)
LabEx grant : 63 332 €
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Role of planar polarity proteins on the cytoskeleton dynamics of dendritic spines
Investigators : Montcouquiol/Sans (NCM), Thoumine (IINS)
LabEx grant : 63 332 €
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Study of miRNA expression pattern as diagnostic and prognostic biomarker in Amyotrophic Lateral Sclerosis
Investigators : Favereaux (IINS), Le Masson (NCM), Wielanek-Bachelet (Centre référence SLA)
LabEx grant : 88 000 €
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The impact of structural changes in axons on information transfert in CA3 neurons:a combined computational and nanoscale imaging study
Investigators : Cattaert (INCIA), Nägerl (IINS)
LabEx grant : 20 000 €
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Thermo-sensitive nanoparticules as a carrier of bioactive peptide against pain sensitization Determining the mode of binding of PSD-95 tandem PDZ domains
Investigators : Landry (IINS), Heroguez (CNRS UMR 5629), Petry (INSERM U1049)
LabEx grant : 86 600 €
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Translational study of the cerebral substrates involved in pathological fear recovery
Investigators : Herry (NCM), Bonnet (UMS CNRS 3428)
LabEx grant : 70 000 €
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- 2012
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Biobanque
Investigators : Bézard (IMN), Meissner (IMN)
LabEx grant : 50 000 €
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Characterization of molecular pathways involved in vulnerability to drug addiction
Investigators : Revest (NCM)
LabEx grant : 40 000 €
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Characterization of neuronal circuits involved in addiction
Investigators : Herry (NCM)
LabEx grant : 40 000 €
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CytoPlan : Impact of planar polarity on shaping neurons and synapses
Investigators : Montcouquiol/ Sans (NCM), Thoumine (IINS)
LabEx grant : 36 000 €
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Dippal : Diagnostic précoce et pléothérapie de la maladie d'Alzheimer
Investigators : Orgogozo (SanPsy), Philip (SanPsy)
LabEx grant : 45 000 €
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Functional contribution of newly born neurons to the formation of remote memories during normal aging
Investigators : Abrous (NCM), Bontempi (IMN)
LabEx grant : 70 014 €
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Morpho-functional plasticity of the tripartite synapse
Investigators : Marsicano (NCM), Nägerl (IINS), Oliet (NCM)
LabEx grant : 58 000 €
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Programming support for dynamic clamp hybrid systems applications
Investigators : Simmers (INCIA), Lemasson (NCM), Cattaert (INCIA)
LabEx grant : 68 000 €
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Psychobehavioral characterization of addiction
Investigators : Cota (NCM), Deroche-Gamonet (SanPsy)
LabEx grant : 20 000 €
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SCOAL : Sleep, cognition and Alzheimer
Investigators : Philip (SanPsy)
LabEx grant : 45 000 €
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Unraveling the anatomical wiring diagram to understand the physiology and pathophysiology of the hippocampus and neocortex
Investigators : Mulle (IINS), Frick (NCM)
LabEx grant : 116 000 €
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